Amanirenas, the famous warrior queen of classical-era Kush, faces off against a Roman legionary in her war against the (newly rechristened) Empire between 27 and 22 BC. It would have been quite a bloody and devastating affair for both sides of the conflict. The Kushites started with a successful attack upon Syene and Philae in the south of Roman-controlled Egypt, but the Romans retaliated with enough force that they managed to sack Napata, the second of Kush’s three historic capitals (its first and third being Kerma and Meroe, respectively).
After this particular war ended, the Roman and Kushite civilizations would not clash that often anymore. The peace treaty between the two powers in 21 or 20 BC conceded most of the Roman territorial gains during the earlier war back to Kush, and the Kushites received an exemption from taxation to Rome. From that point on, the Roman Empire and the kingdom of Kush would enjoy a relatively peaceful coexistence next to one another until the latter declined as a power after 300 AD.